The following article has been submitted to the present ETAI area.   Charalampos Karagiannidis and Constantine Stephanidis: Run-Time Adaptation in Intelligent User Interfaces: Automatic, Iterative Decision Making with Feedback. Abstract: In this paper, we address run-time adaptation in intelligent user interfaces. We adopt a decision theoretic framework, where adaptation is treated as a decision making process, i.e. the user interface selects amongst a set of alternative adaptation constituents, in order to satisfy trade-offs between a set of design goals. We propose that, following this decision-theoretic framework, run-time adaptation is an iterative decision making process, which can automatically utilise continuous feedback concerning the state of user-computer interaction, and we argue that this fact has significant impact on the success of run-time adaptation.